Fluoroquinolones are synthetic antibacterial drugs that have gained popularity because they are effective against many Gram-positive and Gram-negative bacteria. They are often compared to other “second-line” antibiotics, including tetracyclines and macrolides. In this article, we will discuss the side effects of fluoroquinolones.
Nerve Damage
Nerve damage is a severe side effect of fluoroquinolones, especially in patients with kidney or liver impairment. It is so severe that it can lead to permanent disability and even death. This nerve damage occurs when the drug enters the body and damages the nerves in its passage through the kidneys and liver. This nerve damage can be caused by high doses of fluoroquinolones or by long-term drug use. It may also occur if you have diabetes, which causes your kidneys to work less efficiently than usual.
Tendon Rupture
Tendon rupture is another profound side effect of fluoroquinolones that occurs when used for long periods or in high doses. This tendon injury can occur with any type of tendon injury from surgery or sports injuries. Still, it is more likely to occur with long-term antibiotic usage than most other types of tendon injuries because these drugs are often used to treat many different types of bacterial infections (including ear infections). These medications can cause inflammation around tendons, which also leads to inflammation in surrounding tissues.
Aortic Dissection/Aneurysms
Quinolones are associated with an increased incidence of aortic dissection and aneurysms, which is thought to be a primary cause of quinolone-associated aortic complications. The risk is highest in people who have had repetitive courses of quinolones or cephalosporins.
Retinal Detachment
A small percentage of patients taking fluoroquinolones develop retinal detachments (RD). The risk appears to be higher in older adults and those with diabetes, although there is not enough data for these groups to be considered at higher risk for RD. Although most cases are asymptomatic, some patients will require surgical intervention.
Joint and muscle pain
Fluoroquinolones are known to cause rashes in some people. In addition, fluoroquinolones can cause an increased risk of tendon rupture and tendonitis.
Fluoroquinolone antibiotics can also cause tendonitis in your wrists, elbows, fingers and shoulders. Fluoroquinolone antibiotics can also cause tendonitis in your feet. If you have tendonitis in these areas, you should see a doctor immediately so your condition can be treated before it worsens.
Wrapping Up
Some of these side effects are dangerous to the point that they have resulted in life-threatening situations. It is essential to take this drug exactly as your doctor prescribes and never exceed the dosage. If you experience any of these side effects while taking this medication, stop taking it immediately and contact your physician immediately. For others the side effects are relatively mild and don’t require much medical intervention.